Looking for: Does prednisone affect hair texture.What Is the Connection between Prednisone and Hair Loss? Click here - Prednisone and the effect it will have on a perm Weight gain is usually the most dreaded side—effects of steroids, incurred to some degree by nearly all patients who take them. The amount of weight gain varies from individual to individual. In addition to causing weight gain, prednisone leads to a redistribution of body fat to places that are undesirable, particularly the face, back of the neck, and abdomen. Pictured below is an example of redistribution of body fat to the back of the neck. In addition to this redistribution of fat, many patients undergo loss of muscle strength muscle atrophy while taking steroids. Regular physical exercise is key to avoiding this type of deconditioning that often occurs with prednisone treatment. High blood sugar, or steroid—induced diabetes. This usually resolves when the steroids are decreased ...